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2504.17268

Parameter estimation in ODE models with certified polynomial system solving ⋆

Alexander Demin, Alexey Ovchinnikov, Fabrice Rouillier

incompletemedium confidence
Category
Not specified
Journal tier
Specialist/Solid
Processed
Sep 28, 2025, 12:56 AM

Audit review

The paper’s toy example states the 4×4 quadratic system has only two solutions and reports (μ, x0) ≈ (0.49, 1.00) and (0.25, −2.00), explicitly noting this is a heuristic illustration without a rigorous analysis. The candidate solution gives a complete algebraic derivation using the system’s triangular structure, proving exactly two solutions and finding the exact pairs (μ, x0) = (0.50, 1.00) and (0.25, −2.00). The paper’s qualitative claim (two solutions) matches, but it neither supplies a proof nor the exact μ = 0.50 for x0 = 1.00; thus, the paper is incomplete while the model is correct .

Referee report (LaTeX)

\textbf{Recommendation:} minor revisions

\textbf{Journal Tier:} specialist/solid

\textbf{Justification:}

The paper compellingly demonstrates that certified RUR-based solvers can be competitive and sometimes superior to homotopy continuation for polynomial systems arising from ODE parameter estimation. The toy example is illustrative but would benefit from a brief rigorous derivation and exact numerics; otherwise, the narrative is clear and the empirical benchmarking useful. These edits are minor and do not affect the conclusions.